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Thecoma

 
Medical Dictionary: the·co·ma
(thē-kō')
n.

A tumor derived from ovarian mesenchyme and consisting chiefly of spindle-shaped cells that frequently contain small droplets of fat; it may form considerable quantities of estrogens, causing development of secondary sexual features in prepubertal girls or endometrial hyperplasia in older individuals. Also called theca-cell tumor.

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Theca cell tumor.

Wikipedia: Thecoma
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Thecoma
Classification and external resources

High magnification micrograph of a thecoma. H&E stain.
ICD-9 220
ICD-O: 8600
eMedicine / 
MeSH [1]

Thecomas or theca cell tumors are benign ovarian neoplasms composed only of theca cells. Histogenetically they are classified as sex cord-stromal tumours.

They are typically estrogen-producing and they occur in older women (mean age 59; 84% after menopause). (They can, however, appear before menopause.[1])

Sixty percent of patients present with abnormal uterine bleeding, and 20% have endometrial carcinoma.

Pathologic features

Low magnification micrograph of a thecoma showing compression of the ovarian cortex (right of image). H&E stain.

Grossly, the tumour is solid and yellow.

Grossly and microscopically, it compress of the ovarian cortex.

Microscopically, the tumour cells have abundant lipid-filled cytoplasm.


References



 
 
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Luteoma
Compound nevus
Junctional nevus

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Copyrights:

Medical Dictionary. The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company Read more
Veterinary Dictionary. Saunders Comprehensive Veterinary Dictionary 3rd Edition. Copyright © 2007 by D.C. Blood, V.P. Studdert and C.C. Gay, Elsevier. All rights reserved.  Read more
Wikipedia. This article is licensed under the Creative Commons Attribution/Share-Alike License. It uses material from the Wikipedia article "Thecoma" Read more