Thyroidectomy is a surgical procedure in which all or part of the thyroid gland is removed. The thyroid gland is located in the forward part of the neck (anterior) just under the skin and in front of the Adam's apple.
Description
Thyroidectomy is an operative procedure done most commonly by a general surgeon, or occasionally by an otolaryngologist, in the operating room of a hospital. The operation begins when an anesthesiologist puts the patient to sleep. The anesthesiologist injects drugs into the patient's veins and then places an airway tube in the windpipe to ventilate (provide air for) the patient. The surgeon makes an incision in the front of the neck where a tight-fitting necklace would rest. He locates and takes care not to injure the parathyroid glands and the recurrent laryngeal nerves, while freeing the thyroid gland from these surrounding structures. The blood supply to the portion of the thyroid gland that is to be removed is clamped off. Then all or part of the gland is removed. If cancer is present, all, or almost all, of the gland is removed. If other diseases or a nodule is present, the surgeon may remove only part of the gland. The total amount of thyroid gland removed depends upon the thyroid disease being treated. A drain (a soft plastic tube that drains fluid out of the area) may be placed before the incision is closed. The incision is closed either with sutures (stitches) or metal clips. A dressing is placed over the incision and the drain, if one is used.
Patients generally stay in the hospital one to four days after completion of the operation.
Who Performs the Procedure and Where Is It Performed?
Thyroidectomies are usually performed by surgeons with specialized training in otolaryngology, head and neck surgery. Occasionally, a general surgeon will perform a thyroidectomy. The procedure is performed in a hospital under general anesthesia.
Questions to Ask the Doctor
Which parts of the thyroid will be removed?
What will my neck look like after surgery?
Is the surgeon a board certified otolaryngologist?
How many radical neck procedures has the surgeon performed?
What is the surgeon's complication rate?
Will I need any medications after surgery?
Definition
Thyroidectomy is a surgical procedure in which all or part of the thyroid gland is removed. The thyroid gland is located in the forward (anterior) part of the neck just under the skin and in front of the Adam's apple. The thyroid is one of the body's endocrine glands, which means that it secretes its products inside the body, into the blood or lymph. The thyroid produces several hormones that have two primary functions: they increase the synthesis of proteins in most of the body's tissues, and they raise the level of the body's oxygen consumption.
To remove the thyroid gland, an incision is made at the front of the neck (A). Muscles and connecting tissue, or fascia, are divided (B). The veins and arteries above and below the thyroid are severed (C), and the gland is removed in two parts (D). The tissues and muscles are repaired before the skin incision is closed (E). (Illustration by GGS Inc.)
Purpose
All or part of the thyroid gland may be removed to correct a variety of abnormalities. If a person has a goiter, which is an enlargement of the thyroid gland that causes swelling in the front of the neck, the swollen gland may cause difficulties with swallowing or breathing. Hyperthyroidism (overactivity of the thyroid gland) produces hypermetabolism, a condition in which the body uses abnormal amounts of oxygen, nutrients, and other materials. A thyroidectomy may be performed if the hypermetabolism cannot be adequately controlled by medication, or if the condition occurs in a child or pregnant woman. Both cancerous and noncancerous tumors (frequently called nodules) may develop in the thyroid gland. These growths must be removed, in addition to some or all of the gland itself.
Demographics
Screening tests indicate that about 6% of the United States population has some disturbance of thyroid function, but many people with mildly abnormal levels of thyroid hormone do not have any disease symptoms. It is estimated that between 12 and 15 million people in the United States and Canada are receiving treatment for thyroid disorders as of 2002. In 2001, there were approximately 34,500 thyroidectomies performed in the United States. Females are somewhat more likely than males to require a thyroidectomy.
Description
A thyroidectomy begins with general anesthesia administered by an anesthesiologist. The anesthesiologist injects drugs into the patient's veins and then places an airway tube in the windpipe to ventilate (provide air for) the person during the operation. After the patient has been anesthetized, the surgeon makes an incision in the front of the neck at the level where a tight-fitting necklace would rest. The surgeon locates and takes care not to injure the parathyroid glands and the recurrent laryngeal nerves, while freeing the thyroid gland from these surrounding structures. The next step is clamping off the blood supply to the portion of the thyroid gland that is to be removed. Next, the surgeon removes all or part of the gland. If cancer has been diagnosed, all or most of the gland is removed. If other diseases or nodules are present, the surgeon may remove only part of the gland. The total amount of glandular tissue removed depends on the condition being treated. The surgeon may place a drain, which is a soft plastic tube that allows tissue fluids to flow out of an area, before closing the incision. The incision is closed with either sutures (stitches) or metal clips. A dressing is placed over the incision and the drain, if one has been placed.
People generally stay in the hospital one to four days after a thyroidectomy.
Diagnosis/Preparation
Thyroid disorders do not always develop rapidly; in some cases, the patient's symptoms may be subtle or difficult to distinguish from the symptoms of other disorders. Patients suffering from hypothyroidism are sometimes misdiagnosed as having a psychiatric depression. Before a thyroidectomy is performed, a variety of tests and studies are usually required to determine the nature of the thyroid disease. Laboratory analysis of blood determines the levels of active thyroid hormones circulating in the body. The most common test is a blood test that measures the level of thyroid-stimulating hormone (TSH) in the bloodstream. Sonograms and computed tomography scans (CT scans) help to determine the size of the thyroid gland and location of abnormalities. A nuclear medicine scan may be used to assess thyroid function or to evaluate the condition of a thyroid nodule, but it is not considered a routine test. A needle biopsy of an abnormality or aspiration (removal by suction) of fluid from the thyroid gland may also be performed to help determine the diagnosis.
If the diagnosis is hyperthyroidism, a person may be asked to take antithyroid medication or iodides before the operation. Continued treatment with antithyroid drugs may be the treatment of choice. Otherwise, no other special procedure must be followed prior to the operation.
Aftercare
A thyroidectomy incision requires little to no care after the dressing is removed. The area may be bathed gently with a mild soap. The sutures or the metal clips are removed three to seven days after the operation.
Risks
There are definite risks associated with the procedure. The thyroid gland should be removed only if there is a pressing reason or medical condition that requires it.
As with all operations, people who are obese, smoke, or have poor nutrition are at greater risk for developing complications related to the general anesthetic itself.
Hoarseness or voice loss may develop if the recurrent laryngeal nerve is injured or destroyed during the operation. Nerve damage is more apt to occur in people who have large goiters or cancerous tumors.
Hypoparathyroidism (underfunctioning of the parathyroid glands) can occur if the parathyroid glands are injured or removed at the time of the thyroidectomy. Hypoparathyroidism is characterized by a drop in blood calcium levels resulting in muscle cramps and twitching.
Hypothyroidism (underfunctioning of the thyroid gland) can occur if all or nearly all of the thyroid gland is removed. Complete removal, however, may be intentional when the patient is diagnosed with cancer. If a person's thyroid levels remain low, thyroid replacement medications may be required for the rest of his or her life.
A hematoma is a collection of blood in an organ or tissue, caused by a break in the wall of a blood vessel. The neck and the area surrounding the thyroid gland have a rich supply of blood vessels. Bleeding in the area of the operation may occur and be difficult to control or stop. If a hematoma occurs in this part of the body, it may be life-threatening. As the hematoma enlarges, it may obstruct the airway and cause a person to stop breathing. If a hematoma does develop in the neck, the surgeon may need to perform drainage to clear the airway.
Wound infections can occur. If they do, the incision is drained, and there are usually no serious consequences.
Normal Results
Most patients are discharged from the hospital one to four days after a thyroidectomy. Most resume their normal activities two weeks after the operation. People who have cancer may require subsequent treatment by an oncologist or endocrinologist.
Morbidity and Mortality Rates
The mortality of thyroidectomy is essentially zero. Hypothyroidism is thought to occur in 12–50% of persons in the first year after a thyroidectomy. Late-onset hypothyroidism develops among an additional 1–3% of persons each year. Although hypothyroidism may recur many years after a partial thyroidectomy, 43% of recurrences occur within five years.
Mortality from thyroid storm, an uncommon complication of thyroidectomy, is in the range of 20–30%. Thyroid storm is characterized by fever, weakness and wasting of the muscles, enlargement of the liver, restlessness, mood swings, change in mental status, and in some cases, coma. Thyroid storm is a medical emergency requiring immediate treatment. After a partial thyroidectomy, thyroid function returns to normal in 90–98% of persons.
Alternatives
Injections of radioactive iodine were used to destroy thyroid tissue in the past. This alternative is rarely performed in 2003.
Bland, K. I., W. G. Cioffi, and M. G. Sarr. Practice of GeneralSurgery. Philadelphia, PA: Saunders, 2001.
Ruggieri, P. A Simple Guide to Thyroid Disorders: From Diagnosis to Treatment. Omaha, NE: Addicus Books, 2003.
Saheen, O. H. Thyroid Surgery. Boca Raton, FL: CRC Press, 2002.
Schwartz, S. I., J. E. Fischer, F. C. Spencer, et al. Principles ofSurgery, 7th ed. New York: McGraw-Hill, 1998.
Townsend, C., K. L. Mattox, R. D. Beauchamp, et al. Sabiston's Review of Surgery, 3rd ed. Philadelphia, PA: Saunders, 2001.
Periodicals
Bellantone, R., C. P. Lombardi, M. Raffaelli, et al. "Is Routine Supplementation Therapy (Calcium and Vitamin D) Useful After Total Thyroidectomy?" Surgery 132 (December 2002): 1109-1113.
Dror, A., M. Salim, and R. Yoseph. "Sutureless Thyroidectomy Using Electrothermal System: A New Technique." Journal of Laryngology and Otology 117 (March 2003):198-201.
Ikeda, Y., H. Takami, Y. Sasaki. "Clinical Benefits in Endoscopic Thyroidectomy by the Axillary Approach." Journal of the American College of Surgery 196 (February 2003): 189-195.
Oey, I. F., B. D. Richardson, and D. A. Waller. "Video-Assisted Thoracoscopic Thyroidectomy for Obstructive Sleep Apnoea." Respiratory Medicine 97 (February 2003): 192-193.
Organizations
American Academy of Otolaryngology-Head and Neck Surgery. One Prince St., Alexandria, VA 22314-3357. (703) 836-4444. www.entnet.org/index2.cfm.
American College of Surgeons. 633 North St. Clair Street, Chicago, IL 60611-3231. (312) 202-5000; FAX: (312) 202-5001. www.facs.org.
American Medical Association. 515 N. State Street, Chicago, IL 60610. (312) 464-5000. www.ama-assn.org.
American Osteopathic College of Otolaryngology-Head and Neck Surgery. 405 W. Grand Avenue, Dayton, OH 45405. (937) 222-8820 or (800) 455-9404; FAX (937) 222-8840. Email: info@aocoohns.org.
Association of Thyroid Surgeons. 717 Buena Vista St., Ventura, CA 93001, FAX: (509) 479-8678. www.thyroidsurgery.org.
A thyroidectomy operation that involves the surgical removal of all or part of the thyroid gland. Surgeons often perform a thyroidectomy when a patient has thyroid cancer or some other condition of the thyroid gland (such as hyperthyroidism). Other indications for surgery include cosmetic (very enlarged thyroid), or symptomatic obstruction (causing difficulties in swallowing or breathing). One of the complications of "thyroidectomy" is voice change and patients are strongly advised to only be operated on by surgeons who protect the voice by using electronic nerve monitoring.
After the removal of a thyroid patients usually take prescribed oral synthetic thyroid hormones to prevent the most serious manifestations of the resultant hypothyroidism.
Less extreme variants of thyroidectomy include:
"hemithyroidectomy" (or "unilateral lobectomy") -- removing only half of the thyroid
"isthmectomy" -- removing the band of tissue (or isthmus) connecting the two lobes of the thyroid
A "thyroidectomy" should not be confused with a "thyroidotomy" ("thyrotomy"), which is a cutting into (-otomy) the thyroid, not a removal (-ectomy) of it. A thyroidotomy can be performed to get access for a median laryngotomy, or to perform a biopsy. (Although technically a biopsy involves removing some tissue, it is more frequently categorized as an -otomy than an -ectomy because the volume of tissue removed is minuscule.)
Laryngeal nerve injury in about 1% of patients, in particular the recurrent laryngeal nerve: Unilateral damage results in a hoarse voice. Bilateral damage presents as laryngeal obstruction on removal of the tracheal tube and is a surgical emergency: an emergency tracheostomy must be performed. Recurrent Laryngeal nerve injury may occur during the ligature of the inferior thyroid artery.
Hypoparathyroidism temporary (transient) in many patients, but permanent in about 1-4% of patients
