tolerance

(tŏl'ər-əns)
n.

1. The capacity for or the practice of recognizing and respecting the beliefs or practices of others.
2. 1. Leeway for variation from a standard.
   2. The permissible deviation from a specified value of a structural dimension, often expressed as a percent.
3. The capacity to endure hardship or pain.
4. Medicine.
   1. Physiological resistance to a toxin.
   2. Diminution in the physiological response to a drug that occurs after continued use, necessitating larger doses to produce a given response.
5. 1. Acceptance of a tissue graft or transplant without immunological rejection.
   2. Unresponsiveness to an antigen that normally produces an immunological reaction.
6. The ability of an organism to resist or survive infection by a parasitic or pathogenic organism.

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Amount of variation permitted or “tolerated” in the size of a machine part. Manufacturing variables make it impossible to produce a part of exact dimensions; hence the designer must be satisfied with manufactured parts that are between a maximum size and a minimum size. Tolerance is the difference between maximum and minimum limits of a basic dimension. For instance, in a shaft and hole fit, when the hole is a minimum size and the shaft is a maximum, the clearance will be the smallest, and when the hole is the maximum size and the shaft the minimum, the clearance will be the largest.

If the initial dimension placed on the drawing represents the size of the part that would be used if it could be made exactly to size, then a consideration of the operating conditions of the pair of mating surfaces shows that a variation in one direction from the ideal would be more dangerous than a variation in the opposite direction. The dimensional tolerance should be in the less dangerous direction. This method of stating tolerance is called unilateral tolerance and has largely displaced bilateral tolerance, in which variations are given from a basic line in plus and minus values.

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noun

1. Forbearing or lenient treatment: charitableness, charity, forbearance, indulgence, lenience, leniency, lenity, toleration. See accept/reject.
2. The capacity of enduring hardship or inconvenience without complaint: forbearance, long-suffering, patience, resignation. See accept/reject.

n

Definition: fortitude, grit
Antonyms: intolerance, weakness

n

Definition: open-mindedness
Antonyms: bias, disapproval, intolerance, narrow-mindedness, prejudice

The reduction or loss of the normal response to a drug or other substance that usually provokes a reaction in the body. Tolerance may develop after taking a particular drug over a long period of time. In such cases the dosage of the drug may need to be increased in order to produce the desired effect. Examples of drugs that bring about tolerance are ephedrine (used in nasal decongestants), glyceryl trinitrate (for treating angina), and opioids (used for pain relief). Tolerance does not imply dependence, although some drugs that cause tolerance also cause dependence.

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The ability of an organism to survive environmental conditions. The prefixes eury- and steno- refer to wide and narrow ranges of tolerance respectively. An organism can be widely tolerant of one factor, such as temperature (eurythermal), but narrowly tolerant of another, such as salinity (stenohaline).

The permissible deviation in a specified size or dimension.

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1. The capacity to endure pain or hardship, such as harsh environmental conditions or psychological stress.

2. Condition in which increasing doses of a drug are required to maintain the same response. See also drug tolerance.

3. Failure of a body to mount a specific immune response against a particular antigen. Such immunological tolerance usually results from the body having difficulty distinguishing between its own materials that should be tolerated, and foreign materials that should be attacked by antibodies.

Permissable deviation from a specified value normally expressed as a percentage.

IN BRIEF: A disposition to allow freedom of choice and behavior.

In the practice of tolerance, one's enemy is the best teacher. — Dalai Lama

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Quotes:

"Toleration is good for all, or it is good for none." - Edmund Burke

"There is a limit at which forbearance ceases to be a virtue." - Edmund Burke

"Persecution was at least a sign of personal interest. Tolerance is composed of nine parts of apathy to one of brotherly love." - Frank Moore Colby

"I have seen great intolerance shown in support of tolerance." - Samuel Taylor Coleridge

"As no roads are so rough as those that have just been mended, so no sinners are so intolerant as those that have just turned saints." - Charles Caleb Colton

"Travel teaches tolerance." - Benjamin Disraeli

See more famous quotes about Tolerance

1. the progressive attenuation of the response to an agent (usually a drug) whereby increasing concentrations of the agent are required to maintain the response. Underlying mechanisms confer either functional (or pharmacodynamic) tolerance, where the loss of response is due to desensitization of effector mechanisms, or metabolic (or pharmacokinetic) tolerance, whereby elimination of the agent is accelerated usually by induction of catabolic enzymes or other inactivating mechanism.
2. the ability of an organism to grow and thrive in an unfavourable environment.
3. an allowable deviation from a standard.
4. immunological tolerance.

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(tol′ərəns)
n

The ability to endure the influence of a drug or poison, particularly acquired by continued use of the substance. See also resistance.

For a list of words related to tolerance, see:

• Afflictions and Conditions - tolerance: lessening of normal response to drug or other substance taken over a prolonged period, requiring increased dosages for normal reaction
• Physiology - tolerance: diminished response due to repeated exposure
• PHARMACOLOGY - tolerance: decreased effectiveness of drug due to prolonged or repeated use, requiring larger dose for same effect
• Attitudes and Behavior - tolerance: liberal attitude toward differing lifestyles, cultures, and beliefs
• Paraphernalia and Behavior - tolerance: resistance to the effects of a drug, resulting in the need to use increasingly large doses of that drug for the same effect

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See words rhyming with "tolerance."

  See crossword solutions for the clue Tolerance.

Common misspelling(s) of tolerance

• tolerence

Dansk (Danish)
n. - tolerance, frisindethed

Nederlands (Dutch)
verdraagzaamheid, het te verdragen maximum

Français (French)
n. - (Méd) tolérance, (Phys, Tech) résistance, (Math, Stat) marge de tolérance

Deutsch (German)
n. - Toleranz, Duldsamkeit, Nachsicht, Widerstandsfähigkeit, zulässige Abweichung

Ελληνική (Greek)
n. - ανοχή, ανεκτικότητα, μακροθυμία

Italiano (Italian)
tolleranza

Português (Portuguese)
n. - paciência (f), tolerância (f)

Русский (Russian)
терпимость, способность переносить (жару/холод/трудности)

Español (Spanish)
n. - tolerancia

Svenska (Swedish)
n. - tolerans, fördragsamhet, vidsynthet

中文（简体）(Chinese (Simplified))
宽容, 宽大, 公差, 容限, 忍耐, 忍耐力, 耐受性, 耐药量

中文（繁體）(Chinese (Traditional))
n. - 寬容, 寬大, 公差, 容限, 忍耐, 忍耐力, 耐受性, 耐藥量

한국어 (Korean)
n. - 관대, 내성, 공차

日本語 (Japanese)
n. - 寛容, 公差, 辛抱, 耐性, 許容度, 我慢, 許容誤差

العربيه (Arabic)
‏(الاسم) ألقدرة على أحتمال ( أو مقاومه) عقار أو سم, ألأحتمال, تسامح‏

עברית (Hebrew)
n. - ‮סובלנות, סיבולת, כוח-סבל, סטייה מותרת בתכונה מדידה כלשהי, היחלשות התגובה לסם לאחר שימוש ממושך‬

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