| collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital) | |
|---|---|
| Identifiers | |
| Symbol | COL2A1 |
| Alt. symbols | SEDC |
| Entrez | 1280 |
| HUGO | 2200 |
| OMIM | 120140 |
| RefSeq | NM_001844 |
| UniProt | P02458 |
| Other data | |
| Locus | Chr. 12 q13.11-q13.2 |
Type-II collagen is the basis for articular cartilage and hyaline cartilage.
It makes up 50% of all protein in cartilage and 85-90% of collagen of articular cartilage.
Type II collagen does form fibrils. This fibrillar network of collagen allows cartilage to entrap the proteoglycan aggregate as well as provide tensile strength to the tissue.
See also
External links
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