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Urticaria pigmentosa (present alone without systemic disease) also dramatically clears or improves as adolescence approaches.

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Urticaria pigmentosa (present alone without systemic disease) also dramatically clears or improves as adolescence approaches.

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Urticaria pigmentosa(also known as "Generalized eruption of cutaneous mastocytosis (childhood type)":616 ) is the most common form of cutaneous mastocytosis. It is a rare disease caused by excessive numbers of mast cells in the skin that produce hives or lesions on the skin when irritated.
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These skin lesions itch when stroked and may become fluid-filled.

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Many patients with systemic mastocytosis also develop urticaria pigmentosa.

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Mastocytoma and urticaria pigmentosa rarely if ever, develop into systemic mastocytosis, and both spontaneously improve over time.

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