It is the combination of platinum-based (cisplatin, carboplatin) chemotherapy AND docetaxel, paclitaxel, vinorelbine, gemcitabine or irinotecan ... based chemotherapy.

...platinum-doublet chemotherapy (Carboplatin AUC 6+Paclitaxel 200mg/m2 day1 Q3w, Cisplatin 80mg/m2 day1+Irinotecan 60mg/m2 day1,8,15 Q4W, Cisplatin 80mg/m2 day1+Vinorelbine 25mg/m2 day1,8 Q3W, Cisplatin 80mg/m2 + Docetaxel 60mg/m2 day1 Q3W, or Cisplatin 80mg/m2 day1+Gemcitabine 1,000mg/m2 day1, 8 Q3W) up to 6 cycles ...

Taxol belongs to a class of chemotherapy drugs called plant alkaloids. Plant alkaloids are made from plants. The vinca alkaloids are made from the periwinkle plant (catharanthus rosea). The taxanes are made from the bark of the Pacific Yew tree (taxus). The vinca alkaloids and taxanes are also known as antimicrotubule agents. The podophyllotoxins are derived from the May Apple plant. Camptothecan analogs are derived from the Asian "Happy Tree" (Camptotheca acuminata). Podophyllotoxins and camptothecan analogs are also known as topoisomerase inhibitors. The plant alkaloids are cell-cycle specific. This means they attack the cells during various phases of division. * Vinca alkaloids: Vincristine, Vinblastine and Vinorelbine. * Taxanes: Taxol and Docetaxel. * Podophyllotoxins: Etoposide and Tenisopide. * Camptothecan analogs: Irinotecan and Topotecan. Antimicrotubule agents (such as Taxol), inhibit the microtubule structures within the cell. Microtubules are part of the cell's apparatus for dividing and replicating itself. Inhibition of these structures ultimately results in cell death. I hope this helps

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