Results for Yersinia enterocolitica
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Dental Dictionary:

Yersinia enterocolitica

(yursin′-ē-əen′tər-ō-kō-lit′ik-ə)
n.pl

Bacteria that causes Yersinia enterocolitis, contracted from contaminated food or water. Symptoms of infection often mimic acute appendicitis and are most common in children younger than age 7. A sister bacteria, Yersinia pestis, was the cause of the historic bubonic plague.

 
 
Medical Dictionary: Yersinia en·ter·o·co·lit·i·ca
(ĕn'tərō-kō-lĭt'ĭ-kə)
n.

A bacterium that causes yersiniosis.

 
Wikipedia: Yersinia enterocolitica
Yersinia enterocolitica
Yersinia enterocolitica colonies growing on XLD agar plates.
Yersinia enterocolitica colonies growing on XLD agar plates.
Scientific classification
Kingdom: Bacteria
Phylum: Proteobacteria
Class: Gamma Proteobacteria
Order: Enterobacteriales
Family: Enterobacteriaceae
Genus: Yersinia
Species: Y. enterocolitica
Binomial name
Yersinia enterocolitica
(Schleifstein & Coleman 1939)

Yersinia enterocolitica is a species of gram-negative coccobacillus-shaped bacterium, belonging to the family Enterobacteriaceae. Primarily a zoonotic disease (cattle, deer, pigs, and birds), animals which recover frequently become asymptomatic carriers of the disease.[1]

Pathogenesis

Acute infections

Acute Y. enterocolitica infections produce severe diarrhea in humans, along with Peyer's patch necrosis, chronic lymphadenopathy, and hepatic or splenic abscesses. Additional symptoms may include entero-colitis, fever, mesenteric adenitis, erythema nodosum and acute terminal ileitis, which may be confused with appendicitis or Crohn's disease. See yersiniosis for further details.

Treatment

Treatment of Y. enterocolitica infections requires aggressive antibiotic therapy, typically involving a combination of chloramphenicol, ampicillin, and polymyxin.[1]

Long-term effects

Y. enterocolitica infections are sometimes followed by chronic inflammatory diseases such as arthritis.[2]

Y. enterocolitica seems to be associated with autoimmune Graves-Basedow thyroiditis.[3] Whilst indirect evidence exists, direct causative evidence is limited,[4] and Y. enterocolitica is probably not a major cause of this disease, but may contribute to the development of thyroid autoimmunity arising for other reasons in genetically susceptible individuals.[5] It has also been suggested that Y. enterocolitica infection is not the cause of auto-immune thyroid disease, but rather is only an associated condition; with both having a shared inherited susceptibility.[6] More recently the role for Y. enterocolitica has been disputed.[7]

External Links

Footnotes

  1. ^ a b Collins FM (1996). Pasteurella, Yersinia, and Francisella. In: Barron's Medical Microbiology (Barron S et al, eds.), 4th ed., Univ of Texas Medical Branch. (via NCBI Bookshelf) ISBN 0-9631172-1-1. 
  2. ^ Ryan KJ; Ray CG (editors) (2004). Sherris Medical Microbiology, 4th ed., McGraw Hill. ISBN 0-8385-8529-9. 
  3. ^ Benvenga S, Santarpia L, Trimarchi F, Guarneri F (2006). "Human Thyroid Autoantigens and Proteins of Yersinia and Borrelia Share Amino Acid Sequence Homology That Includes Binding Motifs to HLA-DR Molecules and T-Cell Receptor". Thyroid 16 (3): 225-236. PubMed. 
  4. ^ Tomer Y, Davies T (1993). "Infection, thyroid disease, and autoimmunity." (PDF). Endocr Rev 14 (1): 107-20. PMID 8491150. 
  5. ^ Toivanen P, Toivanen A (1994). "Does Yersinia induce autoimmunity?". Int Arch Allergy Immunol 104 (2): 107-11. PMID 8199453. 
  6. ^ Strieder T, Wenzel B, Prummel M, Tijssen J, Wiersinga W (2003). "Increased prevalence of antibodies to enteropathogenic Yersinia enterocolitica virulence proteins in relatives of patients with autoimmune thyroid disease.". Clin Exp Immunol 132 (2): 278-82. PMID 12699417. 
  7. ^ Hansen P, Wenzel B, Brix T, Hegedüs L (2006). "Yersinia enterocolitica infection does not confer an increased risk of thyroid antibodies: evidence from a Danish twin study.". Clin Exp Immunol 146 (1): 32-8. PMID 16968395. 

 
 

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Copyrights:

Dental Dictionary. Mosby's Dental Dictionary. Copyright © 2004 by Elsevier, Inc. All rights reserved.  Read more
Medical Dictionary. The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company Read more
Wikipedia. This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Yersinia enterocolitica" Read more

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