Currently, inside a regular desktop PC the largest unit of size
would be 1 TB (1000 GB), and with this unit it becomes very
difficult to completely fill the storage device.
However, potentially, the largest is the yobibyte, which is a
whopping 10,000,000,000,000,000,000 bits of data. Basically, if
scaled down into human language it would be the information
capacity of the observational universe, meaning every bit of known
knowledge ever recorded, translated into every language and coppied
10,000,000 times over.