by definition ld50 is when 50% survive or dead,,answer will be 5 if i count well
Lethal dose 50, the dosage at which 50% of animals (usually rabbits, I think) given the chemical die as a result of toxicity.
aspirin 81mg
81mg is the common dosage for "baby" aspirin
Insects have higher LD50 for radiation exposure than mammals. LD50 is defined as the dose of something toxic that results in 50% fatality in the exposed group. However insects would have similar problems to mammals surviving the thermal effects.
Poisons are rated by LD50, the dose that kills 50% of a population. The dose can be increased to an LD90, LD99 or whatever but you can never guarantee that the dose will kill them all, as some individuals are more resistant to a specific poison than others are.To get the last few highly resistant individuals may require a dose many orders of magnitude larger than the LD50.
LD50 measures the lethal dose of a substance that causes death in 50% of the test subjects, typically expressed in milligrams of substance per kilogram of body weight. It provides a standardized way to compare the toxicity of different substances.
LD50 (lethal dose for 50% of the population) should be greater than ED50 (effective dose for 50% of the population) to ensure safety in drug administration. A higher LD50 indicates a larger margin between the dose that produces a therapeutic effect and the dose that can cause harm or death. This distinction is crucial for minimizing the risk of toxicity and ensuring that a drug can be used effectively without endangering the patient's life. In essence, a greater LD50 compared to ED50 indicates a safer therapeutic window.
The human lethal dose of sodium chloride (LD50) is 3 g NaCl/kg body.
The 'median lethal dose'. In other words, the average dose that would be enough to kill you
The LD50 of phenobarbital in humans is estimated to be around 15 mg/kg when taken orally. LD50 represents the dose at which 50% of the test population would die as a result of the substance.
Calculating the median lethal dose, LD50 (the dose of a toxin which kills half of the test population) first requires a lot of laboratory testing which can take months. The data is then accumulated and manipulated to give a value which is the median dose. -- Why don't you get to understand Lichfield wilcoxon's method.
LD50 ('50%-Lethality' dose) is a meaured value from many statical investigations. So there's only a good definition on how it should be 'measured' and can not be calculated from other values by formula.