Our world is facing a depletion of several natural resources.
Continued use of aerosol cans will lead to depletion of the ozone layer.
The chlorine in chlorofluorocarbons causes depletion of atmospheric ozone.
Example sentence - The rapid depletion of the natural resources is happening at an accelerated rate.
Deplete
To have used up the supply of something
The fish in the aquarium developed gill disease, due to ozone depletion in the filter system.
"Setback", "prevention", and "depletion" don't seem to go together in the rest of the sentence. Are you asking "what do we get by preventing ozone depletion?" Maybe you meant "payback", rather than "setback". Otherwise, see the related questions section below.
A SENTENCE WITH THE WORD OUNCE A SENTENCE WITH THE WORD OUNCE A SENTENCE WITH THE WORD OUNCE A SENTENCE WITH THE WORD OUNCE
a sentence with the word variety
Chlorofluorocarbons are thought to deteriorate the ozone.
The word is sentence
This sentence is a sentence with the word "consolation" in it.