0
What else can I help you with?
What enzyme strips hydrogen atoms from organic molecules?
Cytochrome P450 enzymes are known to strip hydrogen atoms from organic molecules as part of metabolic processes, such as drug metabolism.
A common drug for the treatment of tuberculosis is known to markedly interfere in the metabolism of?
isoniazid
Are SSRI enzyme inducers or inhibitors?
The SSRIs can be both CYP450 enzyme inhibitors AND inducers. Inhibitors inhibit the metabolism of drugs, causing the body to have increased levels of that drug. Inducers speed of the metabolism of a drug, causing the body to inactivate/eliminate to a further extent than it normally would. It depends on which SSRI you are talking about. They all have actions on various isoforms of CYP450, but the SSRIs which cause the greatest problems with inhibition/inducing are fluoxetine (Prozac) and paroxetine. (Paxil)
When was Drug Metabolism Reviews created?
Drug Metabolism Reviews was created in 1972.
Where does drug metabolism occur?
Drug metabolism primarily occurs in the liver, where enzymes break down drugs into metabolites that can be excreted from the body. Other organs, such as the kidneys and intestines, also play a role in drug metabolism to some extent.
What drug speeds up your metabolism?
The drug that you use!~
Is there a difference between enzyme inhibition and enzyme suppression?
enzyme induction: Many of the enzymes involved in drug metabolism may be up-regulated by exposure to drugs and environmental chemicals leading to increased rates of metabolism. This phenomenon is known as enzyme induction Enzyme inhibition: Inhibiting the activity of enzymes(generally done by heating, changing Ph, reaction with different chemicals.)
Is Alkaline Phosphate a CYP450 enzyme?
No, alkaline phosphatase is not a CYP450 enzyme. Alkaline phosphatase is an enzyme involved in removing phosphate groups from organic molecules, while CYP450 enzymes are a family of enzymes involved in the oxidation of organic substances in the body, including drug metabolism.
What is cytochrome P-450 used for?
The family of liver isoenzymes known as cytochrome P-450 are crucial to drug metabolism
What drugs slow drug metabolism?
Drugs that slow drug metabolism include ciprofloxacin, erythromycin, fluoxetine, nefazodone, paroxetine, and ritonavir
What factors determine a drug's rate of metabolism?
How quickly a drug clears from the body is a function of its absorption, bioavailability, distribution, metabolism, and excretion properties.
What is the difference between first pass and phase one of drug metabolism?
First pass metabolism refers to the metabolism of a drug that occurs in the liver after it is absorbed from the gastrointestinal tract, before it enters systemic circulation. Phase 1 metabolism is the initial biotransformation of a drug, primarily carried out by enzymes such as cytochrome P450, to make the drug more polar and easier to eliminate from the body.
