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Reptiles have 2 body openings. Mouth and an anus.
Females have the openings for the vagina, urethra, and anus.
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The famous animal the "Porifera", has 6 body openings.
By them entering through openings in the body.
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* yes, or they would have no place to procreate or give birth. * NOT all of them. Mostly Vertebrate animals