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I believe you are referring to "Aventil" which is one of the brand names for Nortriptyline, a tricyclic anti-depressant.

Tricyclic anti-depressants have been used for decades as a preventative medication for migraines. It is also used for chronic daily headache, as well as other types of chronic pain. Amitriptyline (brand name: Elavil) is more often used to treat trigeminal and occipital neuralgia than Nortriptyline.

Recent studies have shown tricyclic anti-depressants to provide at least as much benefit as the more recent preventative medications used to treat migraines and other chronic headaches, even against medications which have become very popular to prescribe, such as Topamax.

Tricyclic anti-depressants work for chronic daily headaches the same way other types of anti-depressants do - by working with serotonin levels. Normally taken before bedtime, it has also been shown to promote sleep, which is something lacking when people are in chronic pain. Improved amounts of healthy sleep can improve a person's ability to cope with pain.

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Q: Anybody hear of this avental for chronic muscular headaches?
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