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Call the great nephew Joe and the great aunt Pamela.

If Pamela is the sister of Joe's grandmother or grandfather, then Joe and Pamela are "blood relatives."

However, Pamela could be the wife of a brother of one of Joe's grandmother's or grandfathers and still be Joe's great aunt. In that case, Pam and Joe are not "blood relatives."

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14y ago
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16y ago

They can be, but they are not necessarily so. I can have grand nephews and nieces who are the grandchildren of my brother (my sibling), and I can have grand nephews and nieces who are the grandchildren of my wife's sister. These two sets of nephews and nieces are not blood related. When you visit your aunt and uncle (married to each other) you are related to only one of them by blood. They are still your aunt and uncle.

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13y ago

Your grandchild and your nephew are 1st cousins once removed.

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13y ago

Your great niece and your great grandson are second cousins, once removed.

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12y ago

Your Great-Aunt/uncle, would be your parent's aunt/uncle.

So, your grand nieces would be your nieces kids, and plus their kids would make you their Great-Great-Aunt/Uncle.

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15y ago

2nd cousins?

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14y ago

no

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Q: Are grand nieces and grand nephews blood related?
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