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Yes.
Sucralose is a non-nutritive sweetener. many people prefer this non-nutritive sweetener to avoid gaining excessive weight or the disease known as diabetes caused by an excessive use of natural sweeteners which leads to your pancreas not functioning properly with the lack of insulin.
DRUGDEX
Yes, Skin Medica is a brand of skincare products that has been FDA approved. The FDA regulates certain aspects of skincare products, such as ensuring they meet safety and labeling requirements. However, it's important to note that FDA approval does not necessarily mean that a skincare product is more effective or superior to non-FDA approved products.
Some have "non-nutritive sweeteners" such as sorbitol and mannitol, and others have the common artificial sweeteners saccharin or aspartame (Nutrasweet). The use of L-sugars (non-digestible molecular forms) is fairly rare because they are much more expensive, and can have an unintended laxative effect because they hold water.
medical drug reference
The three main examples of non nutritive components are fibers, flavors, and colors.
DRUGDEX by Micromedex
Dimenhydrinate is a medication used for the treatment and prevention of motion sickness. A non-FDA labeled indication (not an indication approved by the FDA, but often used for by Physicians) also indicates the medication for postoperative nausea and vomiting treatment and prevention.
Sand, rock, wood, and other such non-edible stuff.
non FDA approved drugs
Diapulse is "pulsed, non-thermal, high peak power, electromagnetic energy, indicated for post operative edema, and chronic and acute wounds. Approved by both FDA and Medicare.