Are there any misspelled words in the Constitution?

NO

But remember, the accepted spelling of some words has changed over the last 2 centuries. The one in the Constitution that stands out is "chuse" instead of "choose". And if you follow its example for the use of capital letters, you'll get an F in English composition!

YES

DEFENCE instead of DEFENSE

CONTROUL instead of CONTROL

IT's instead of ITS in atricle 1

PENSYLVANIA instead of PENNSYLVANIA