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What happens during metaphase stage?

Updated: 8/10/2023
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15y ago

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At metaphase, the nucleus has completely degraded and the chromosomes are all ligned up at the centre of the cell. This line up of chromosomes is called the metaphasic plate. During metaphase, the chromosomes are maximally condensed.

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14y ago
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15y ago

Metaphase, from the ancient Greek μετά (after) and φάσις (stage), is a stage of mitosis in the eukaryotic cell cycle in which condensed chromosomes, carrying genetic information, align in the middle of the cell before being separated into each of the two daughter cells.

Preceded by events in prometaphase and followed by anaphase, microtubules formed in prophase have already found and attached themselves to kinetochores in metaphase. The centromeres of the chromosomes convene themselves on the metaphase plate, an imaginary line that is equidistant from the two centrosome poles. This even alignment is due to the counterbalance of the pulling powers generated by the opposing kinetochores, analogous to a tug of war between equally strong people. In certain types of cells, chromosomes do not line up at the metaphase plate and instead move back and forth between the poles randomly, only roughly lining up along the middleline. Early events of metaphase can coincide with the later events of prometaphase, as chromosomes with connected kinetochores will start the events of metaphase individually before other chromosomes with unconnected kinetochores that are still lingering in the events of prometaphase. One of the cell cycle checkpoints occurs during prometaphase and metaphase. Only after all chromosomes have become aligned at the metaphase plate, when every kinetochore is properly attached to a bundle of microtubules, does the cell enter anaphase. It is thought that unattached or improperly attached kinetochores generate a signal to prevent premature progression to anaphase, even if most of the kinetochores have been attached and most of the chromosomes have been aligned. Such a signal creates the mitotic spindle checkpoint. This would be accomplished by regulation of the Anaphase Promoting Complex, securin, and separase. more information:

http://en.wikipedia.org/wiki/Metaphase

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12y ago

Chromosomes align along equator, or metaphase pate of cell.

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chromosomes align in pairs at the nucleus along the spindle fibres

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Q: What happens during metaphase stage?
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In Metaphase, the chromasomes align along the metaphase plate. Associating the location and the stage may help you remember.


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