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if that 22 rifle is chambered for the 22-250 round

now if your meaning a .22lr (as in marlin mod.60) then NO not even close

prettymuch all .22 short,long or LR are all rimfires the .22-250 is a centerfire round

that packs a nice punch and has a super flat trajectory

Unless your firearm says its chambered for that round then no it will not except it the only exception to this rule is

you can shoot .38 spl. in a .357 (not the other way around)

and the .460S&Wmag will shoot the .444 casuel,.45LC,.44mag

but that's really the only things that you can shoot and be safe that's not labeled

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Q: Can 22 rifle fire 22-250 cartridge?
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22 hornet is a 22 calibre rifle. Most think of a 22 rifle as a rim fire rifle. But it shoots a 22 calibre bullet but the cartridge case that fires the bullet is no where near the same. The Hornet holds much more powder and is center fire.


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No. WRF is a larger diameter cartridge, and does not interchange with .22 LR


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Is 22 WRF same as 22 long rifle?

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