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Yes, in some cases. Adderall contains amphetamine which is a central nervous system stimulant. Tramadol is an opioid used to treat pain. Both medications are known to lower the seizure threshold; combining these two drugs could result in seizures. Consult your physician or medical professional if this combination is safe for you. If your doctor prescribed this combination, he or she has decided that the benefits outweigh the potential risks.

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13y ago
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12y ago

Only in small amounts, like one fioricet and 10 mg adderall. Unless, of course, you have a huge tolerance for both. I wouldn't do it though, and there's not much that I haven't. At least separate the intake by an hour to be safe.

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Q: Can Adderall be taken with Tramadol?
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