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I assume you want to speed off Concerta and then sleep with Tylenol PM? Is that right? Well first, there is no come down from Concerta, it just wears off. The next day, however, is going to be the most boring day of you life. And secondly, have you taken PM before? It suck. I have taken it far too many times. I doesn't put you to sleep, it doesn't make you feel rested, it does nothing. There is nothing to worry about coming down from Concerta.

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Q: Can Concerta and Tylenol be taken together?
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