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No. At least not as of yet. The xbox team has not tuned the emulator enough to run it. They may add it in the future considering it's popularity, but for now your only hope of playing this game is to get an xbox original.

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Q: Can Metal Gear Solid 2 substance work on Xbox 360?
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Does Metal Gear Solid substance Xbox work on Xbox 360s?

No. According to Microsoft, Metal Gear Solid 2: Substance for the Xbox does not have backwards compatibility with the Xbox 360 system. You can however purchase Metal Gear Solid 2: Sons of Liberty as part of the Metal Gear Solid: HD Collection for the Xbox 360.


Is there an official mgs3 for Xbox?

No. The only Metal Gear Solid game available for the Xbox is Metal Gear Solid 2: Substance. However, Metal Gear Solid 3: Subsistence is available for the Xbox 360 as part of the Metal Gear Solid: HD Collection.


Is Metal Gear Solid 3 substance for original xbox?

No. The entire Metal Gear Solid series has been Playstation-exclusive all the way until Rising. Metal Gear Solid Rising will be for Playstation 3 and Xbox 360.


Can you play mgs2 substance on xbox360?

Metal Gear Solid 2: Substance for the Xbox is not playable on the Xbox 360. However, it is available as part of the Metal Gear Solid: HD Collection for the Xbox 360, PlayStation 3, and PlayStation Vita.


Are there any Metal Gear Solid games exept for rising that are for xbox 360?

As of 2012, there exist three Metal Gear Solid games with the exception of Metal Gear Rising: Revengeance for the Microsoft Xbox 360. They are Metal Gear Solid 2: Sons of Liberty, Metal Gear Solid 3: Snake Eater, and Metal Gear Solid: Peace Walker. They are part of the Metal Gear Solid: HD Collection, and can also now be purchased separately.


Is metal gear solid 4 going on xbox 360?

As of 2013, there are no plans to release Metal Gear Solid 4: Guns of the Patriots on the Xbox 360. Metal Gear Solid 4has been announced as part of the Metal Gear Solid: The Legacy Collection on PlayStation 3. Given that the next generation of video game consoles will soon be announced, it is unlikely that Metal Gear Solid 4 will be adapted for the Xbox 360 system.


Will Metal Gear Solid the rising for the ps3?

Yes. Metal Gear Solid: RISING will be on both the PS3 and the XBOX 360


Is Metal Gear Solid peace walker for xbox 360?

No, Metal Gear Solid: Peace Walker is a PSP exclusive.


Metal gear solid 5?

As of now, there is no Metal Gear Solid 5. However, Metal Gear Solid: Rising is coming out for the Xbox 360 and PlayStation 3 with an unconfirmed release date. Metal Gear Solid: Peace Walker will be on the PSP, and will be released May 25th of this year.


Is 'Metal Gear Solid' for the original Xbox too?

No. The game Metal Gear Solid is not for XBOX. Only MGS: Sons of Liberty is for XBOX. Although you can get the remake (although pretty rare) Metal Gear Solid: The Twin Snakes for Nintendo Gamecube. It has updated graphics and voice acting and a few other added features that makes it a little easier to play.


When is Metal Gear Solid 4 guns of the patriots coming out for XBox 360?

Sorry to burst your bubble, but the answer is never. However, if you own the Xbox and want to play a Metal Gear on it, well, take heart in the fact that a new Metal Gear game (Metal Gear Rising) will come out for both the Xbox and the PS3...


What does Metal Gear Solid HD consist of?

The Metal Gear Solid: HD Collection consists of either two or three games. In Japan, the HD Collection is made up of Metal Gear Solid 2: Sons of Liberty and Metal Gear Solid 3: Snake Eater, upscaled to HDTV resolution. It is available for the PlayStation 3, Xbox 360, and PlayStation Vita. In America, the PlayStation 3 and Xbox 360 versions of the HD Collection also come with an upscaled version of Metal Gear Solid: Peace Walker.