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No. Promethazine has no "pain killing" properties. It is used for nausea, vomiting, and some other acute upper Gastrointestinal symptoms.

A little further detail it is a antihistamine antiemetic, and acts on H1 histamine receptors, so it can be used as an allergy medication although due to its Rx status its is very uncommon.

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Q: Can Promethazine be used for tooth aches?
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