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yes! I've taken it twice with the same result- not involuntary, but i could not lie still, and even felt the need to 'shake out' my hands and feet every minute or two- absolutely miserable because i really needed to sleep, but it was impossible for approx 3 hrs. also have had this reaction to NyQuil- not sure if it uses the same ingredient or not.

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Q: Can Tylenol pm cause severe jerking of the body when you are trying to go to sleep?
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