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Methadone is administered for relief of pain in horses and dogs. Analgesia peaks between 10 and 20 minutes post-administration and persists three to five hours.

In dogs, methadone is used in premedication of barbiturate anaesthesia. Barbiturates have extremely poor analgesic properties, even at high dose rates. Methadone premedication of barbiturate anaesthesia smoothes induction and greatly minimises the risk of drug toxicity by enabling the dose of barbiturate to be halved.

It is still recommended to first see a veterinarian to receive proper instruction on how to go about treating your dogs pain.

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