Yes.
It means that you made matters worse by saying or doing something that inflamed the situation even worse than it already was.
Applying ginger to inflamed skin is not the best idea. This is because ginger is a spice and can actually make the inflamed skin worse. Aloe Vera will help inflamed skin.
knock that person out so you can get yourself out.
This is the same as me, I had an open operation under General and had an inflamed appendix removed. It has now been 5 days and still no bowel movement. It is very uncomfortable and is made worse with food. I am reluctant to take a laxative as I want things to get back to normal. Hopefully this is just part of the healing process.
no cause it makes it worse.
It is normal, but if the pain continues and it gets worse see a doctor.
The word "worse" is already the comparative of the word "bad". If you are looking for a superlative in connection to "worse" the answer is "worst".
since I've been taking them I've had about 7 pop up in there, it bloody hurts worse than my appendix did!!
aggravate:to make worse or more severe; intensify, as anything evil, disorderly or troublesome.to annoy; irritate, exasperate.to cause to become irritated or inflamed.
To make matters worse, the poster's spelling was incorrect.
Yes you can. You can get MUCH worse than it already is. 
I thought they already had. You mean it's going to get worse?