Can a licenced 16 year old drive from pa to Florida?

In Florida, you have to be 16 and have your regular license. Keep in mind, areas along that route, such as Atlanta and many areas of Florida have some pretty extreme traffic. The driver would need to have the experience to navigate it what is difficult for many people that have been driving for several years.

Yes. However, I would not suggest they try it. At 16 you have not accumulated experience in driving. All main roads will have VERY heavy traffic.