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Q: Can a person have muscular dystrophy with normal CPK?
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What is the significance of a slightly elevated creatine kinase blood test presumed not cardiac related?

cpk enzymes are found in cardiac muscle, skeletal muscle and the brain, cpk will be elevated 10 to 25 times the normal level following a myocardial infarction, they will also be elevated after a trauma to skeletal muscle and in progressive muscular dystrophy, cpk can be elevated after strenuous exercise.


Does fibromyalgia cause elevated CPK Lab results?

At this time there has been no connection between elevated CPK results and Fibromyalgia. Abnormal CPK results may be indicitive of a number of conditions, including: inflammation of the muscle of the heart, heart attack, stroke, inflammation of the skeletal muscles, muscular dystrophy, death of muscular tissue, convulsions, and hypothyroidism.


What causes cpk level to be high?

CPK is an enzyme that stands for Creatine Phospho Kinase. It is elevated in :Myocardial infarction (MI),Myocarditis,Traumatic Muscle injury,Rhabdomyolysis,Muscular dystrophy,Myositis, polymyositis, Dermatomyositis, Myopathy,Severe muscular exertion,Malignant hyperthermia,Hypothyroidism,Cerebral infarction,Surgery,Reye syndrome,Tetanus,Convulsions,IM injections,Alcoholism,DC Shock.Drugs: clofibrate, HMG-CoA reductase inhibitors like Simvastatin


What is a normal blood creatinine phophokinase level?

A normal creatine phosphokinase (CPK) level is anywhere from 10 to 120 micrograms per liter (mg/L). CPK is released when a muscle is damaged and can show whether a person has had a heart attack.


What is a normal CPK rate?

Creatinine-phosphate-kinase is an enzyme found in heart and muscle. Normal blood CPK range is 38-174 units/L


What does cpk mean in a blood test?

creatine phosphate kinase. it increases in heart disease & muscular disease.


Is a cpk level of 197 abnormal?

just borderline but normal


Is Cholesterol related to CPK?

No cholesterol is obtained from food or synthesized by the liver as a fatty source of both calories and hormones. CPK, or creatine phosphokinase, is an enzyme in muscles which increase in the bloodstream at times of muscular overuse or injury.


Muscular dystrophy?

DefinitionDuchenne muscular dystrophy is an inherited disorder that involves rapidly worsening muscle weakness.Alternative NamesPseudohypertrophic muscular dystrophy; Muscular dystrophy - Duchenne typeCauses, incidence, and risk factorsDuchenne muscular dystrophy is a rapidly-worsening form of muscular dystrophy. Other muscular dystrophies (including Becker's muscular dystrophy) get worse much more slowly.Duchenne muscular dystrophy is caused by a defective gene for dystrophin (a protein in the muscles). However, it often occurs in people without a known family history of the condition.Because of the way the disease is inherited, males are more likely to develop symptoms than are women. The sons of females who are carriers of the disease (women with a defective gene but no symptoms themselves) each have a 50% chance of having the disease. The daughters each have a 50% chance of being carriers.Duchenne muscular dystrophy occurs in approximately 1 out of every 3,600 male infants. Because this is an inherited disorder, risks include a family history of Duchenne muscular dystrophy.SymptomsSymptoms usually appear before age 6 and may appear as early as infancy. They may include:FatigueMental retardation (possible, but does not worsen over time)Muscle weakness Begins in the legs and pelvis, but also occurs less severely in the arms, neck, and other areas of the bodyDifficulty with motor skills (running, hopping, jumping)Frequent fallsRapidly worsening weaknessProgressive difficulty walkingAbility to walk may be lost by age 12By age 10, the person may need braces for walking. By age 12, most patients are confined to a wheelchair.Signs and testsA complete nervous system (neurological), heart, lung, and muscle exam may show:Abnormal heart muscle (cardiomyopathy)Congestive heart failure or irregular heart rhythm (arrhythmias) -- rareDeformities of the chest and back (scoliosis)Enlarged calf muscles, which are eventually replaced by fat and connective tissue (pseudohypertrophy)Loss of muscle mass (wasting)Muscle contractures in the heels, legsMuscle deformitiesRespiratory disorders, including pneumonia and aspiration of food or fluid into the lungs (in late stages of the disease)Tests may include:Electromyography (EMG)Genetic testsMuscle biopsySerum CPKTreatmentThere is no known cure for Duchenne muscular dystrophy. Treatment aims to control symptoms to maximize quality of life. Gene therapy may become available in the future.Activity is encouraged. Inactivity (such as bedrest) can worsen the muscle disease. Physical therapy may be helpful to maintain muscle strength and function. Orthopedic appliances (such as braces and wheelchairs) may improve mobility and the ability to care for yourself.Support GroupsYou can ease the stress of illness by joining a support group where members share common experiences and problems. See muscular dystrophy - support group. The Muscular Dystrophy Association is an excellent source of information on this disease.Expectations (prognosis)Duchenne muscular dystrophy leads to quickly worsening disability. Death usually occurs by age 25, typically from lung disorders.ComplicationsCardiomyopathyCongestive heart failure (rare)DeformitiesHeart arrhythmias (rare)Mental impairment (varies, usually minimal)Permanent, progressive disability Decreased mobilityDecreased ability to care for selfPneumonia or other respiratory infectionsRespiratory failureCalling your health care providerCall your health care provider if:Your child has symptoms of Duchenne muscular dystrophySymptoms worsen, or new symptoms develop, particularly fever with cough or breathing difficultiesPreventionGenetic counseling is advised if there is a family history of the disorder. Duchenne muscular dystrophy can be detected with about 95% accuracy by genetic studies performed during pregnancy.ReferencesKliegman RM, Behrman RE, Jenson HB, Stanton BF. Muscular dystrophies. In: Kliegman RM, Behrman RE, Jenson HB, Stanton BF. Nelson Textbook of Pediatrics. 18th ed. Philadelphia, Pa:Saunders Elsevier; 2007:chap 608.


List of abbreviation for 'Cpk'?

Cpk = Cp (Process Capability) + p (katayori) Japanese for deviation. Cpk = Deviation of process capability


What does the medical abbreviation CPK mean?

CPK means creatine phosphokinase. It's sometimes abbreviated CK. CPK testing is often used to evaluate chest pain.


What is the definition of Cp and Cpk in Statistical process control?

Cp is the capability of a process and Cpk is the actual capability of a part running in the process. The only way Cp = Cpk is if the process mean is exactly centered which is seldom the case in manufacturing. Therefore, Cp > or = to Cpk.