Yes, it is an inherited disorder.
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Sickle-cell anemia can only be transmitted if both partners have the disease.
The disease is recessive, requiring both parents to carry the allele for the disease to be found in the offspring. If one parent has it, the offspring can also be a carrier, but it will be recessive, and the offspring will have normal RBC (red blood cells)
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A person can only inherit sickle-cell genes if some of their ancestors came from certain regions in Africa where the inhabitants carry sickle-cell genes. A person with one sickle-cell gene has sickle-cell trait, a milder problem. If both father and mother pass on sickle-cell genes, the child, with two genes, will have sickle-cell disease.
The person is homozygous for the trait
No, sickle cell anemia and sickle cell trait are not the same. Sickle cell anemia is a severe form of the disease caused by inheriting two sickle cell genes (one from each parent), leading to significant health complications. In contrast, sickle cell trait occurs when an individual inherits only one sickle cell gene and one normal gene, typically resulting in no symptoms but allowing the person to pass the trait to their offspring.
Sickle cell trait and sickle cell disease are both genetic conditions caused by a mutation in the hemoglobin gene. Sickle cell trait means a person carries one copy of the mutated gene, while sickle cell disease means a person has two copies. The key distinction is that individuals with sickle cell trait usually do not experience symptoms, while those with sickle cell disease can have severe health issues such as pain crises, anemia, and organ damage.
A person with one sickle cell is a "carrier". This means that they have the dormant cell in their genetic composition, and if combined with another with the "carrier" gene, they run the high risk on concieving a child with the blood disease-one who has two sickle cells. A person with two sickle cells, has the sickle cell disease and are carriers(The gene is not dormant but active). Hope this simplifies and explains it for you.
The person is homozygous for the trait
No, sickle cell disease is not cancerous.
No. Sickle Cell is not an infectious disease, but is genetic.