If she has proper grip with the large sharp knife and has some muscles, yes.
Another Answer
There are many, many variables involved in such an encounter. The large cat is designed to hunt. It has long sharp claws attached to powerful limbs, as well as long sharp teeth attached to powerful jaws. If you can avoid these items coming into contact with your body during the encounter, putting you into shock, you have a chance to impart killing damage. Of course you have to know what damage will kill the animal as well. Anyone can kill a large cat with a foot long sharp stick if inserted through one eye deep into the brain. Being close enough, fast enough, and accurate enough to push the stick through the eye into the brain is the hard part.
YES!
The large cat, a tiger, has sharp retractable claws on each of its four paws. It doesn't have nails in its fur.
they probably be pretty sharp and nasty looking. they can probably be hurtful and evil and can bite through anything you give them. They're as sharp as the blade of a knife and can cut through any kind of meat, even last nights steak :) lol
really really sharp
sharp ones
The Tasmanian tiger, more properly known as a Thylacine, was a carnivorous marsupial; therefore, it needed to have very sharp teeth.
Sharp teeth and sharp claws
the white tiger avoids danger with it's sharp teeth and markings.
they hear like a dog
Sharp curve or edge
It is possible for a woman to defeat a tiger by shooting it down with a rifle before the tiger charges to attack. She can also kill a tiger with a good enough knife when the tiger is not attacking.
The only difference between a regular tiger and a white tiger is colour. Having said that, yes a white tiger has sharp teeth, just like any other tiger would.