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In short, no.

The four blood groups (A, B, AB, and O) describe the type of sugars that are present (expressed) on the red blood cells that carry oxygen. There are two types of sugar - A and B. If a person is AB, they express both A and B sugars, while type O individuals do not express any sugars. Since the father and mother each contribute one of their sugar genes to a baby, the possible combinations of genes and sugars are:

blood type AB = one A + one B

type A = A+A or A+O

type B = B+B or B+O

type O = O+O

Therefore, a type A baby must have at least one parent who expresses the type A sugar, although that parent can have either an AB or A blood type.

On the other hand, it is possible for two people with type A blood to have a child with type O, if both parents have the (A+O) combination and pass on the O.

This is also why determining the blood type is so important for transfusions - for example, you cannot give a person with type O blood any other type of blood. Since the type O recipient's immune system was not "trained" to accept the A or B sugars as a normal part of the red blood cells, it would think there is something wrong with the transferred cells and kill them.

Positive/negative is a different gene, and requires at least one parent to be positive for the child to be positive.

HTH!

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Q: Can an O positive mother and O positive father have A positive baby?
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