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No. You can only safely fire the correct caliber from each handgun. For instance, for a .40 caliber handgun, you can only fire .40 ammunition. There are some minor exceptions, mostly in revolvers. For instance, you can fire .38 special or .357 magnum from a revolver that will fire .357 magnum, but not the other way around.

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Q: Can any pistol cartridges be fired from any handgun?
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Is a pistol a handgun yes or no?

Yes, pistols are handguns, and so are revolvers. Technically, "pistol" refers to a semi-automatic and revolver refers to a revolver, but people typically use pistol to refer to any handgun.


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