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It's thankfully not common, but it does occasionally happen. There have been brief, sharp epidemics of various strains of bird flu that have become transmittable to humans. That's one of the biggest fears of many epidemiologists; that some strain of bird flu will mutate into a form that people can catch.

In fact, that's one of the major plot lines in John Ringo's best-selling military thriller "The Last Centurion"; that a strain of bird flu becomes an epidemic, killing billions of people.

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