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the activity of the enzyme UDP-glucuronyl transferase is low in the newborns.so UDP- glucuronic acid for conjugation is limited. this leads to high level of unconjugated bilirubin (beyond 25mg/dl) .it may cross the blood brain barrier resulting in hyperbilirubinemic toxic encephalopathy or kernicterus .
prevention aspects:
the drug phenobarbital is used, as it induce bilirubin metabolising enzymes in liver.
in some neonates blood transfusion may be necessaryto prevent brain damage.
phototherapy is continuously carried out till the serum bilirubin becomes normal.
phototheraphy deals with the exposure of the jaundiced neonates to blue light as bilirubin absorbs the blue light and get converted to non toxic lumirubin and get excreted.
What else can I help you with?
Which types of jaundice can be prevented by vaccination?
Vaccines for hepatitis A, hepatitis B, and yellow fever can prevent jaundice due to viral infection.
What abnormal skin colors result from liver disorders?
Jaundice
Is infant jaundice fatal?
Infant jaundice can be fatal if untreated. Most infants recover.
Who discovered jaundice?
John Dice discovered Jaundice.
What substance is responsible for jaundice?
what substance is responsible for the jaundice
Is Jaundice spread?
Jaundice is spread by impure water.
Did Ernest Hemingway have jaundice?
Ernest Hemingway did have jaundice at one point of his life. He was hospitalized in Milan because of bad jaundice.
What is a yellow discoloration of the skin caused by greater-than-normal amounts of bilirubon in the blood is known as?
jaundice
Medical condition starts with j?
Jellinek's disease jaundice
Is Jaundice an adverse effects of antipsychotic agents?
yes, obstructive jaundice.
Is it possible to have jaundice and not know it or is it more or less obvious?
Yes, it is possible to have jaundice and not know. However, these are doing the very early stages of jaundice.
Can you get jaundice by kissing?
Jaundice is a descriptive term for yellow skin. Your skin won't turn yellow from kissing someone. If the cause of their jaundice is an infectious diease, you may contract it from kissing. The viral hepatitis infections are not spread by kissing.
