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Can jaundice be prevented

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Anonymous

13y ago
Updated: 5/18/2022

the activity of the enzyme UDP-glucuronyl transferase is low in the newborns.so UDP- glucuronic acid for conjugation is limited. this leads to high level of unconjugated bilirubin (beyond 25mg/dl) .it may cross the blood brain barrier resulting in hyperbilirubinemic toxic encephalopathy or kernicterus .

prevention aspects:

the drug phenobarbital is used, as it induce bilirubin metabolising enzymes in liver.

in some neonates blood transfusion may be necessaryto prevent brain damage.

phototherapy is continuously carried out till the serum bilirubin becomes normal.

phototheraphy deals with the exposure of the jaundiced neonates to blue light as bilirubin absorbs the blue light and get converted to non toxic lumirubin and get excreted.

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Kathryn Lebsack

Lvl 10
3y ago

What else can I help you with?