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What is the physiology of Waldenstrom's macroglobulinemia?
In WM, the cancerous plasma cells overproduce large amounts of identical (monoclonal) IgM antibody.
Difference between monoclonal antibody and polyclonal antibody?
Polyclonal antibodiesMonoclonal antibodiesInexpensive to produceExpensive to produceTechnology required is lowHigh technology requiredSkills required are lowTraining is required for the technology useTime scale is shortTime scale is long for hybridomasProduces large amounts of non specific antibodiesCan produce large amounts of specific antibodies but may be too specificRecognizes multiple epitopes on any one antigenRecognizes only one epitope on an antigenCan be batch to batch variabilityOnce a hybridoma is made it is a constant and renewable source and all batches will be identical
Which state of India produce large amount of wool?
kashmir
How can you produce large amount of ammonia?
through hoberr process
How were kushites different from the egyptians?
They produce large amount of iron
If the following steps are used to produce monoclonal antibodies What is the fourth step?
1. A mouse is injected with a specific antigen that will induce antibodies against that antigen.2. The spleen of the mouse is removed and homogenized into a cell suspension. The suspension includes B cells that produce antibodies against the injected antigen.3. The spleen cells are mixed with myeloma cells that are capable of continuous growth in culture but have lost the ability to produce antibodies. ( Some of the antibody producing spleen cells and myeloma cells fuse to form hybrid cells. These hybrid cells are now capable of growing continuously in culture while producing antibodies.4. The mixture of cells is placed in a selective medium that allows only hybrid cells to grow.5. Hybrid cells proliferate into clones called hybridomas. The hybridomas are screened for production of the desired antibody.6. The selected hybridomas are then cultured to produce large quantities of monoclonal antibodies.
What is large scale of production?
When a business or a firm produce large amount of production, then it is called large scale of production.
How does a lever apply force with advantage?
It applies a small amount of force to produce a large amount of force.
What diseases are being treated with monoclonal antibodies?
Monoclonal antibodies are commonly used to fight a large number of diseases including cancer. The monoclonal antibodies fight the disease by targeting a certain antigen and recruiting the body's natural immune system to destroy the antigen-infected cells.
What class of antibody forms a large complex that can agglutinate cells?
IgM
Which would cause a gas furnace to produce a large amount of carbon monoxide?
incomplete combustion
Particles or waves given off by atoms undergoing nuclear decay produce?
Produce a large amount of heat and energy which is utilized for many purposes
