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Penicillin is an antibiotic that's becoming more and more common these days. Bacteria are becoming increasingly resistant to it. So the affect it causes on the bacteria actually has to do with what resistance the bacteria strain is.

Coming back to your answer, all antibiotics are known to attack the cell walls (without which a bacterium cannot survive). So if the cell wall isn't present, the bacteria can do no harm and will eventually die. But if it is, the penicillin will destroy it.

so yes

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