possibly hyperparathyroidism. you can see this info on www.parathyroid.com hope this helps out some
possibly hyperparathyroidism. you can see this info on www.parathyroid.com hope this helps out some
Tertiary hyperparathyroidism occurs when CRF causes a severe imbalance in the calcium-phosphate ratio, leading to very high PTH production that results in hypercalcemia. Patients with this condition have high PTH and high calcium levels.
PTH
PTH is released when the body senses low serum calcium levels. PTH does everything in its power to increase serum calcium- it rips it from bone, increases its absorption from food, increases VIT D production (which also aids calcium absorption) and reduces its excretion from the body in urine. It therefore reduces urinary calcium.Above it was stated that PTH increases vit D production.This is wrong. Exposure of the skin to sunlight when the angle isn't too low and certain foods and supplements increase vit D. When serum calcium is low, PTH is sent by the parathyroids to signal vitamin D to activate itself and enable calcium absorption. When there is sufficient dietary calcium and vitamin D, serum calcium rises appropriately, and PTH is then decreased. When there is not enough dietary calcium and vitamin D, PTH can't get the calcium it needs. PTH then goes to the kidneys to look for temporarily stored calcium. If there isn't enough there, it goes to the bone to get the calcium there. Urinary calcium is from excess calcium that is absorbed into the blood with help from vitamin D (and thyroid) or absorbed when the bone is broken down. I learned that when urinary calcium is very high (above 300), PTH is high, but serum calcium is normal, this may indicate primary hyperparathryoidism even if serum calcium is normal. Good luck finding a doctor who will look further into primary hyperparathyroidism for patients without high serum calcium, regardless of high PTH and high urine calcium.
The parathyroid gland produces parathyroid hormone (PTH), which regulates the blood calcium level. When blood calcium is low, PTH is secreted and stimulates the digestion of bone tissue by osteoclasts, this releases calcium from the bone into the bloodstream. Calcitonin has the opposite effect of PTH, and is released from the thyroid gland when blood calcium is too high.
The C-terminal PTH assay is used to diagnose the ongoing disturbances in PTH metabolism that occur with secondary and tertiary hyperparathyroidism.
Calcitonin is an antagonist to PTH C cells increase calcitonin secretion due to high blood Ca levels PTH is secreted due to decrease in Ca level in blood Calcitonin allows osteoclasts to increase bone resorption when blood Ca level decreases.
Drugs that decrease PTH include cimetidine and propranolol.
The assay for intact PTH and the N-terminal fragment, which are both measured at the same time, is more accurate in detecting sudden changes in the PTH level. For this reason, the N-terminal PTH assay is used to monitor a patient's response to therapy.
It is the name of the test used to determine parathyroid hormone (PTH). It stands for ImmunoRadioMetric Assay.
Increased appetite, increased energy, increased sex drive, low blood pressure are NOT symptoms of a PTH deficiency. Symptoms related to a deficiency in parathyroid hormone (PTH) include loss of energy, Osteoporosis and Osteopenia, painful bones, diminished sex drive, heartburn, depression, kidney stones, high blood pressure, and many others.