Can you eat ligers?

Anyone is able to eat anything they can get past their nose and down their throat. The question here was likely intended to be about the legality of eating meat from ligers. Hybrids of protected animals were excluded from the Endangered Species Act of 1973, so ligers and tigons are not protected. Some countries forbid the crossbreeding to produce ligers or tigons, but the United States is not one of them.

USDA does not inspect or regulate lion meat, so it falls to FDA or to the state. Simply, the FDA's stance on game meat is that as long as the species is not on the endangered list and it is produced under safe and wholesome conditions, it is acceptable. The FDA has no voluntary inspection service like the USDA does.

It would appear that in the United States - as long as the meat processor has all his ducks in a row - the production and sale of liger meat for your outdoor barbeque feast would be legal.

There are petitions to change that.