Yes, you can get Mesprit in Pokémon Black 2 and White 2 however this is only possible after beating Iris, the Pokémon League Champion. Once you've beaten her, you can go to the Cave of Being in order to meet with the female Professor Juniper and you'll come across Sinnoh's 3 Pixies (Azelf, Mesprit and Uxie) and then they will depart. Each one will appear somewhere in the region as soon as you step on a specific spot.
For Mesprit, the specific spot you need to step on is on the top of the Celestial Tower, below the stairs.
Additionally if you don't want to catch Mesprit in Black 2 or White 2 then you can use the Poké Transfer Lab in Route 15 in order to transfer a Mesprit you have in a previous game. Pokémon Diamond, Pokémon Pearl, Pokémon Platinum, Pokémon HeartGold and Pokémon SoulSilver are the only games that can be used with Black 2 and White 2's Poké Transfer Lab.
You also have the option of trading with someone that already has Mesprit.
No, you will not be able to find Mesprit in Pokémon Black, you would have to trade with Black 2 or White 2 or you would have to transfer Mesprit from a previous game.
4 because the sell pokemon white and pokemon black and know they sell pokemon white 2 and pokemon black 2
Celestial tower off of Mistralton City, after they escape from the cave
Zekrom. It is Pokemon White's mascot, NOT Pokemon Black's, as a common and logical error states BUT its vise versa in pokemon black 2 and pokemon white 2 so if u want to get a zekrom (advise: hes better) i suddegest pokemon black 2 but pokemon white 2 is a better game
There are 300 Pokemon in the Pokemon Black 2 and White 2 Unova Pokedex.
Black Kyurem is in Pokemon Black 2.
it evolves if you transfer it from Pokemon black or white to Pokemon black 2 or white 2
White 2: White Kyurem Black 2: Black Kyurem Black 2 and White 2: Therian forms of Tornadus, Thunderus and Landorus.
Yes
Pokemon Black 2 and White 2 are coming out on October,7,2012 in America.
black and white 2
Mesprit is in the underground lake.