Can you get a cdl after 2 DUIs in Virginia?

Not as long as the resulting suspension period from your DUI conviction is in effect. If it has passed, and you've reinstated your licence, you can upgrade it to a CDL. If your DUI occurred within the past 10 years, your prospects of finding employment as a CDL driver are slim. If it's been within the past five years, you'd be best advised to pursue another career path, and not waste your money getting a CDL.