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I've answered this exact same question before in relation to tattoos, but in the instance of a piercing; prednisone is an immunosuppressant medication that will possibly effect the healing of the piercing and/or tattoo, so I would hold off on getting it till you are either off of the medication or have switched to a different medication with less of an impact to your immune system. However, the tongue is an area that with proper care will heal quite easily and quickly, so possibly given this you would be able to get the piercing with no adverse reactions. Still though, I would hold off.

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Q: Can you get a tongue piercing while on Prednisone?
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