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On rare occasion, strong spices might cause your urine to burn, but more than likely, strong spices would cause the feces to burn or cause you to urinate more frequently.

If you are referring to detecting the synthetic drug called "spice" in the urine, then more than likely, it will be detected. You won't test positive for cannabis, but since synthetic cannabis is also illegal, there are separate drug tests for it.

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Q: Can you piss hot from spice?
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