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There is a major drug-drug risk when combining these two drugs. They both work on the GABA system, and will amplify each other. Blacking out, doing things that you NEVER would have done otherwise, reckless behavior, and SEVERE respiratory depression (which can be fatal) is a very major threat between these drugs (sedatives) and alcohol. As always, talk to your Doctor or Pharmacist before making any drug changes.

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Q: Can you take Ambien with buspurone and alcohol?
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