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Generally one should avoid the combination as ibuprofen can lead to increased INR and thus raise one's risk of bleeding while on warfarin. If the two are to be combined, it should be done under the supervision of a medical doctor and close monitoring of the patient's INR.

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13y ago
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13y ago

No, you should avoid this combination as long as ibuprofen might interfer with INR and blood coagulation.

You have to use Tylenol (acetaminophen/paracetamol) instead. If you use an anti inflammatory drug, it should be done with medical supervision (INR tests)

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13y ago

Gel give slightly release than tablets but they both work the same way (pharmacologically). My question is why are you mixing them? Ibuprofen is not candy and you can overdose on it resulting in toxic effects or adverse effects (even serious side effects). I would really consult a pharmacist before taking it - medications are tailored to individual patient's situation so there are no general answers.

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13y ago

This combination is not specifically warned against. However, ibuprofen causes your stomach to produce less protective mucus, which increases your chance of stomach problems such as ulcers and heartburn. If you are already taking warfarin, then you should be already aware of the signs of internal bleeding that you should watch out for (tarry black or coffee-ground-like stool, paleness of eyelids or gums, etc.). If you take ibuprofen, which increases the risk for stomach ulcer if taken over a period of time, then you should be especially vigilant and watch for signs of internal bleeding. Reporting these findings to your doctor is of life-saving importance. Reporting your medication regimen to your doctor is also equally important. Only your doctor can tell you with relative certainty if it is safe for you to take ibuprofen with warfarin.

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12y ago

They should not be taken together without your doctor or pharmacist telling you that it is okay. Ibuprofen can stimulate the drop in platelet count in the body, and thus increase your risk of bleeding. Remember that internal bleeding is potentially life threatening. So don't do it unless a pharmacist or doctor tells you that it's okay.

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10y ago

NO! The only over the counter pain medicine that is ok to take with warfarin is Tylenol (acetaminophen).

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11y ago

No, you will die in seven days.

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Q: Can I use ibuprofen gel while on warfarin?
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