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This would be OK. This combination could be used to treat severe allergic reactions such as poison ivy or drug allergy. Remember that the prednisone is very harsh on your stomach. Have food on your stomach when you take each dose! The hydroxyzine will make you drowsy and lightheaded.

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14y ago
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14y ago

There are no drug interactions between these two drugs. However, keep in mind that both drugs are harsh to your stomach. Have a good meal before you take the steroid. If you have heartburn or upset stomach with these, you can take something like Zantac to reduce the stomach acid.

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14y ago

I just did moments ago. So far so good.

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Q: Can you take Prednisone and hydrocodone together?
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