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5-hydroxytryptophan may interact with many other medicines, possibly increasing side effects or resulting in decreased therapeutic effects. Do not take 5-hydroxytryptophan without first talking to your doctor if you are taking any other medicines, especially any of the following: * a monoamine oxidase inhibitor such as tranylcypromine (Nardil), phenelzine (Parnate), or isocarboxazid (Marplan); * a selective serotonin reuptake inhibitor such as citalopram (Celexa), fluvoxamine (Luvox), fluoxetine (Prozac), paroxetine (Paxil), or sertraline (Zoloft); * a tricyclic antidepressant such as amitriptyline (Elavil), amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Sinequan), imipramine (Tofranil), nortriptyline (Pamelor), protriptyline (Vivactil), or trimipramine (Surmontil); * bupropion (Wellbutrin, Zyban); * trazodone (Desyrel) or nefazodone (Serzone); * venlafaxine (Effexor); * mirtazapine (Remeron); * an HIV/AIDS protease inhibitor such as indinavir (Crixivan), amprenavir (Agenerase), nelfinavir (Viracept), ritonavir (Norvir), or saquinavir (Fortovase, Invirase); or * an HIV/AIDS nonnucleoside reverse transcriptase inhibitor such as delavirdine (Rescriptor), efavirenz (Sustiva), or nevirapine (Viramune). You may not be able to take 5-hydroxytryptophan, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above. Drugs other than those listed here may also interact with 5-hydroxytryptophan or affect your condition. Talk to your doctor and pharmacist before taking any other prescription or over-the-counter medicines including vitamins, minerals, and herbal products.

Retrieved 9 Jul 2009

<http://www.drugs.com/mtm/5-hydroxytryptophan.html>

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14y ago
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12y ago

NO. To mix the two could cause serotonin syndrome which can be fatal. If you are not getting enough of an effect from your Zoloft, ask your Doctor to increase the dosage.

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Q: Can you take Zoloft and 5htp?
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