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This would be OK to do. There are no interactions listed between these two drugs. Remember that methotrexate is very harsh on your stomach. Have some food before you take this!

Even more important to remember is that methotrexate wipes out folic acid in the system so a folic acid supplement needs to be taken everyday in order to reduce the risk of liver toxicity.

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13y ago
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6y ago

Looking at the interactions between the two drugs, I would first suggest talking to a pharmacist as they would know best the interactions between the medications.

Meloxicam and methotrexate show the most serious potential interaction, as meloxicam can increase the severity of side effects caused by methotrexate including but not limited to vomiting, diarrhea, swelling of joints, joint pain, rash, loss of appetite, yellow discoloration of skin and eyes, and many more. With this combination, it is particularly important that you consult with the doctor or pharmacist before using them both.

Valtrex and celexa both show the next potentially serious interactions. Valtrex and methotrexate used together increase the risk for damage to the kidneys and celexa and methotrexate used together increase the risk for bleeding. Both of these include some serious side effects, so it's best to consult with someone more knowledgeable.

Again, just to get the point across, I am NOT a doctor or pharmacist. I would highly suggest seeking the help of one of these if you have any questions about any drugs being taken together.

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6y ago

Yes. There doesn't appear to be any interactions, but please consult with a pharmacist or physician to be sure.

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Wiki User

12y ago

no

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