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There are no specific drug interactions between Vicodin (hydrocodone with acetaminophen) and Mucinex (guaifenesin). Drink plenty of water with the Mucinex and remember that the Vicodin can make you drowsy.

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10y ago
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11y ago

I take plain 5mg oxycodone tablets (along with naproxen, when needed) for rheumatoid arthritis pain, and am prescribed 180 tablets per month, or 6 per day.

Percocets are a mixture of either 5 or 7.5 mgs of oxycodone and acetaminophen, aka 'tylenol.'

I also have emphysema and take prescription mucinex as needed--600 mgs extended release tablets twice a day to help loosen phlegm.

(I take many other drugs as well, but you're only asking about percocet and mucinex, haha.)

My doctors and pharmacists check and double-check everything I take for possible adverse interactions, and I've never had a problem with taking them together. In fact, I do so several days a week, more often if I have a cold or am suffering from an R/A flareup.

In the future, know that you can call your local pharmacy to ask these sorts of questions, even if the drugs haven't been prescribed for you. You don't have to give your name, just ask to speak to a pharmacy technician and ask your question.

You're far more likely to get an accurate (and potentially life-saving) answer that way than by asking strangers on the internet.

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12y ago

I've taken it several times before. The only reaction I have is it makes me very sleepy, but I feel well rested in the morning. I don't recommend taking them together while operating a vehicle or machinery. Otherwise doesn't give me any problems.

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14y ago

Mucinex and oxycodone can be taken together.

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14y ago

can i take mucinex with naproxen and vicodin

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Q: Can you take vicodin and mucinex dm?
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Related questions

Is it ok to take mucinex d while taking doxycycline?

can you take doxycycline with mucinex dm


Can you take mucinex if you have glaucoma?

Mucinex DM contains guaifenasin, which shouldn't be taken if you have glaucoma.


Can you take Mucinex DM with Lorazapam and Zolpidam?

Ask your doctor.


Can you take mucinex dm while taking Aleve?

Yes, there is no problem in taking those 2 drugs together.


What happens if you take ONLY twice the recommended amount of Mucinex DM?

You Die


Is mucinex dm safe to take while breastfeeding?

There are some who say it is not safe and others who say it is. The best thing to do is to ask your doctors. Here are the responses: No. Mucinex DM is not safe to take while pregnant. The plain Mucinex without the decongestant (DM) is safe to take. No. Mucinex DM is not safe to take while pregnant. The plain Mucinex without the decongestant (DM) is safe to take. The "DM" portion of the medication is not a decongestant. It stands for Dextromethorphan which is a cough suppressant...and which (in the form of Robitussin DM) is considered safe by many OB doctors. Mucinex DM is safe during pregnancy. Had the same issue today actually. 12 weeks pregnant and unsure of what to take. Went to CVS without my cell so I couldn't call my OB. I asked the pharmacist and he said mucinex DM would be best. He recommended not taking anything with sudafed or phenylephrine in it, which rules out any type of Tylenol cold medicine. Mucinex DM is not a decongestant, its a cough suppressant. Mucinex D is the decongestant. If you're congested and coughing, take the Mucinex DM for the cough and a saline nasal spray for the congestion. Pharmacist recommended method.


Is it ok to take mucinex d and a bc powder?

I took mucinex DM Extra strength 1200mg with BC powder and got really high.


Can you take amox tr-k clv 875 with mucinex dm?

i have taken it while on amoxicillin.


Is mucinex dm still good 5 months past experation date?

No - everything has a shelf life for a reason. Buy new mucinex dm!


Can you take Mucinex DM and Oxycodone together?

I take 225mg of oxycodone per day as prescribed for back pain. Often times,as I live near the beach, the humidity makes my nose feel clogged. I take my nightly dose (75mg) and usually 30 mins later take mucinex DM maximum strength. I have not experienced any problems so far. Of course you should consult ur doc before you begin taking any kind of new meds.


Is it safe to take mucinex dm after its expiration date?

It is not recommended to take Mucines DM after its expiration date. Most medicines have a long shelf life, but they become ineffective after the expiration date.


Does mucinex dm have aspirin in it?

No it doesn't