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An anaphylactic reaction has nothing to do with taking medications together. Anaphylaxis is an allergic reaction caused by your body's response to a certain substance. When you eat or take something you are allergic to, you could have this sort of reaction where your mouth and throat swell up and block your breathing. That is what an anaphylactic reaction.

There are no known drug interactions between naproxen and allopurinol. Unless you are allergic to one of them, you can safely take them together. Take them with food because they can both be hard on the stomach.

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14y ago
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Q: Can you take naproxen and allopurinol together without having an anaphylactic reaction?
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