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You should be very cautious about mixing medications. The best advice is to consult with your doctor before taking any medications, including over the counter medications, in combination.

Not generally.....Naproxen is a NSAID, a non-steroidal anti-inflammatory drug, and Hyrdocodone is a narcotic. You should be careful if taking too much of either, because Naproxen can be damaging to the stomach lining and Hydrocodone is paired with acetaminophen, which can be toxic to the liver in high dosages.

Do not take Tylenol or any other acetaminophen-containing drug when taking Hydrocodone.

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13y ago
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11y ago

Wouldn't recommend it. Speak to your Doctor first.

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14y ago

i dunno about naproxen but 325 mg of hydrocodone seems like alot....32 and a half lorcet tens...???

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11y ago

yes

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Q: Can you take 325 mg hydrocodone 8 hours after taking naproxen?
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