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Yes, but you should check with a doctor or pharmacist to learn if this may cause an ill effect.

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Veda Glover

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2y ago
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12y ago

I asked the pharmacist that question and he said it was fine. I am taking vicotin 5mg and my Allergies are acting up so i am taking 24 hr claritin and i feel fine. If you feel weird about it just call your local Walgreen's and ask the pharmacist on staff.

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Wiki User

10y ago

Taking benadryl 15 minutes or so after taking 2 Norcos (10/325) produces more of a euphoric effect. I have found that the liquid benadryl (just a normal dose) is more effective than 2 benadryl pills.

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14y ago

Officially there's probably not a problem with that. From personal experience though, I took a Zyrtec earlier in the day because I was having allergies and then I took 5 mg Vicodin for my restless leg at night. The Vicodin hit me way harder and it was almost scary. I will not do that again. So be advised the Zyrtec may make the Vicodin stronger. Benedryl will definitely do this, I didn't realize that Zyrtec could.

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13y ago

Benedryl (Diphenhydramine Hydrochloride) and Vicodin (Hydrocodone) should not be mixed together without consulting your Doctor and/or Pharmacist.

The reason for this is that both medications are depressants and can cause severe enough depress to ensure coma and death.

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Q: Can you take Claritin with Valium and vicodin?
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Can you take Valium and claritan?

Yes, Valium can safely be taken with the antihistamine Claritin.


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Vicodin can cause constipation not cure it. It has codeine in it.


Im prescribed adderall xr vicodin and Valium Is this safe?

That doesn't seem very safe. Adderall reacts badly with Diazapam (Valium) but I'm not sure about the Vicodin though, I'm sure you will be fine with that. You might want to talk to your doctor about the Valium and Adderall mixture though, I take adderall too and the part about drug interactions says not to mix with the Diazapam.


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Depending on the dosages, mixing Valium and Vicodin can result in respiratory failure and death. Narcotic pain killers like Vicodin and benzodiazepines like Valium can be a deadly combination.Personal comments:I currently take 30mg of Vicodin per day and 20mg of Valium; however, you should not drive on this level of medications. Also, you should not take them together at the same time.I usually take 30 mg Vicodin in the morning to alleviate my pain and will take 20mg Valium about 8-10 hours later. I have a high tolerance to both meds.Neither medicine should be taken just to get high. Medicines are almost always associated with side effects and often they are serious side effects and some may cause death, especially when they are mixed with other medicines.Always ask a doctor before mixing these medications and see how they affect you before doing even ordinary tasks until you know how these meds will affect you.Always take medications under the supervision of a doctor.


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No there not the same! Hydrocodone is a drug called Hycodan, and Vicodin is a drug called Valium.


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